{"entity":{"id":"nct06706076","kind":"trial","name":"A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations","aka":[],"tldr":"A phase 1/2 trial of Carboplatin, Pemetrexed in non-small-cell lung cancer and small-cell lung cancer, run by BlossomHill Therapeutics, now recruiting.","summary":"A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations is a phase 1/2 interventional study registered as NCT06706076 by BlossomHill Therapeutics, with 675 participants planned, started 2025-01-09 and due to reach its primary completion in 2029-01-31. Interventions recorded: BH-30643, BH-30643 combo therapy with Carboplatin/Pemetrexed, BH-30643. Conditions listed: NSCLC (Advanced Non-small Cell Lung Cancer). No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06706076","url":"https://clinicaltrials.gov/study/NCT06706076"}],"tags":["ctgov-ingest"],"related":[],"cancers":["nsclc","sclc"],"sections":[],"technologies":[],"targets":[],"drugs":["carboplatin","pemetrexed"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT06706076","phase":"1/2","setting":"A Phase 1/2 Open-Label, Multicenter, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of BH-30643 in Adult Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations (SOLARA)","sponsor":"BlossomHill Therapeutics","enrolled":675,"outcomes":[]},"route":"/trials/nct06706076/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"drug":[{"id":"carboplatin","kind":"drug","name":"Carboplatin","route":"/drugs/carboplatin/"},{"id":"pemetrexed","kind":"drug","name":"Pemetrexed","route":"/drugs/pemetrexed/"}]}}