{"entity":{"id":"nct06728072","kind":"trial","name":"Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Virginia Commonwealth University, now recruiting.","summary":"Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer is a phase 2, randomised interventional study registered as NCT06728072 by Virginia Commonwealth University, with a registry enrolment figure of 97 participants, started 2025-03-07 and due to reach its primary completion in 2035-07-01. Interventions recorded: Standard of Care Chemotherapy + Metronidazole, ciprofloxacin, aspirin. Conditions listed: Colorectal Cancer; CRC. Primary outcome: Best response by analysis using Response Evaluation Criteria in Solid Tumors. Colorectal eligibility wording from the registry: \"* Diagnosis of stage IV colorectal cancer\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06728072","url":"https://clinicaltrials.gov/study/NCT06728072"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06728072","phase":"2","setting":"Pilot Study Evaluating Microbiome Modulation Therapy (MBMT) With Ciprofloxacin, Metronidazole, and Aspirin in Addition to Standard of Care Chemotherapy in Patients Undergoing First-Line Therapy for Metastatic Colorectal Cancer","sponsor":"Virginia Commonwealth University","enrolled":97,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06728072/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}