{"entity":{"id":"nct06750861","kind":"trial","name":"QL1706 Plus Chemotherapy With AG Regime as First-line Treatment of Advanced PDAC","aka":[],"tldr":"A phase 2 trial of iparomlimab and tuvonralimab in pancreatic cancer, run by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, not yet recruiting.","summary":"QL1706 Plus Chemotherapy With AG Regime as First-line Treatment of Advanced PDAC is a phase 2, interventional study registered as NCT06750861 by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, with a registry enrolment figure of 30 participants, started 2025-02-15 and due to reach its primary completion in 2026-06-30. Interventions recorded: QL1706. Conditions listed: Pancreatic Adenocarcinoma. Primary outcome: Objective Response Rate (ORR); Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]. Pancreatic eligibility wording from the registry: \"Has histologically or cytologically confirmed pancreatic ductal adenocarcinoma (PDAC);\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06750861","url":"https://clinicaltrials.gov/study/NCT06750861"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac","metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":["iparomlimab-tuvonralimab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06750861","phase":"2","setting":"QL1706 in Combination With Nab-paclitaxel and Gemcitabine as First-line Treatment in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma : A Single-arm, Phase II Study","sponsor":"Cancer Institute and Hospital, Chinese Academy of Medical Sciences","enrolled":30,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06750861/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"},{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"drug":[{"id":"iparomlimab-tuvonralimab","kind":"drug","name":"Iparomlimab and tuvonralimab","route":"/drugs/iparomlimab-tuvonralimab/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}