{"entity":{"id":"nct06757244","kind":"trial","name":"DOVIPA, a Study Evaluating Efficacy and Safety of DOstarlimab and VItamin D3 With mFOLFIRINOX in PAncreatic Cancer","aka":["DOVIPA"],"tldr":"A phase 2 trial of dostarlimab in pancreatic cancer, run by Hopital Foch, now recruiting.","summary":"DOVIPA, a Study Evaluating Efficacy and Safety of DOstarlimab and VItamin D3 With mFOLFIRINOX in PAncreatic Cancer is a phase 2, interventional study registered as NCT06757244 by Hopital Foch, with a registry enrolment figure of 35 participants, started 2025-02-18 and due to reach its primary completion in 2028-02-18. Interventions recorded: Dostarlimab; Vitamin D3 (Cholecalciferol); mFOLFIRINOX Treatment Regimen; LV5FU2. Conditions listed: Pancreas Neoplasms. Primary outcome: Objective response rate (ORR) according to Response Evaluation Criteria version 1.1 (RECIST 1.1) in patients with pancreatic adenocarcinoma and measurable disease. Pancreatic eligibility wording from the registry: \"Histologically confirmed metastatic Stage IV adenocarcinoma of the pancreas\". Sites: France. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06757244","url":"https://clinicaltrials.gov/study/NCT06757244"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["metastatic-pdac"],"sections":[],"technologies":["checkpoint-inhibitor"],"targets":[],"drugs":["dostarlimab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06757244","phase":"2","setting":"DOVIPA, a Phase II Study Evaluating Efficacy and Safety of DOstarlimab and Oral VItamin D3 With Folinic Acid, 5FU, Irinotecan Plus Oxalipaltin (mFOLFIRINOX) in Non Pretreated Metastatic PAncreatic Cancer","sponsor":"Hopital Foch","enrolled":35,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06757244/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"technology":[{"id":"checkpoint-inhibitor","kind":"technology","name":"Immune checkpoint inhibitors","route":"/technologies/checkpoint-inhibitor/"}],"drug":[{"id":"dostarlimab","kind":"drug","name":"Dostarlimab","route":"/drugs/dostarlimab/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}