{"entity":{"id":"nct06769425","kind":"trial","name":"HS-10502 Combination Treatment in Patients With Advanced Solid Tumors","aka":[],"tldr":"This study tests a PARP inhibitor; the registry reports that it is recruiting.","summary":"The registry lists NCT06769425 as recruiting, last updated 2025-06-24. Enrolment is 157 planned participants, an estimate. Interventions: HS-10502 + NHA, HS-10502 + HS-20093, HS-10502+ Apatinib, HS-10502 + HS-20089, HS-10502 + Platinum + Bevacizumab, HS-10502 + nab-paclitaxel or Docetaxel or Irinotecan, HS-10502 + Bevacizumab. Primary measures include Maximum tolerated dose (MTD) of HS-10502（Stage 1：Dose escalating stage）; Maximum applicable dose (MAD) of HS-10502（Stage 1：Dose escalating stage）. No results are posted in the registry; this does not exclude separate publications.","status":"recruiting","asOf":"2026-10-06","links":[{"label":"ClinicalTrials.gov NCT06769425","url":"https://clinicaltrials.gov/study/NCT06769425"}],"tags":[],"related":[],"cancers":["breast-cancer","tnbc","ovarian","prostate","gastric"],"sections":[],"technologies":[],"targets":["parp"],"drugs":["hs-10502"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06769425","phase":"1","setting":"A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of HS-10502 Combination Treatment in Subjects With Advanced Solid Tumors","sponsor":"Jiangsu Hansoh Pharmaceutical Co., Ltd.","started":"2025-05-07","startedType":"actual","enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06769425/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"target":[{"id":"parp","kind":"target","name":"PARP","route":"/targets/parp/"}],"drug":[{"id":"hs-10502","kind":"drug","name":"HS-10502","route":"/drugs/hs-10502/"}]}}