{"entity":{"id":"nct06770439","kind":"trial","name":"IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer","aka":[],"tldr":"A phase 2 trial of IBI343, gemcitabine and nab-paclitaxel in pancreatic cancer, run by Zhejiang University, now recruiting.","summary":"IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer is a phase 2, randomised interventional study registered as NCT06770439 by Zhejiang University, with a registry enrolment figure of 64 participants, started 2025-04-18 and due to reach its primary completion in 2027-01. Interventions recorded: IBI343; Gemcitabine+Albumin-bound paclitaxel. Conditions listed: Advanced Pancreatic Cancers. Primary outcome: Objective Response Rate; Adverse Event. Pancreatic eligibility wording from the registry: \"* Histopathologically confirmed unresectable locally advanced, recurrent, or metastatic pancreatic adenocarcinoma\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06770439","url":"https://clinicaltrials.gov/study/NCT06770439"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac","metastatic-pdac"],"sections":[],"technologies":["adc","cytotoxic-chemotherapy"],"targets":[],"drugs":["ibi343","gemcitabine","nab-paclitaxel"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06770439","phase":"2","setting":"A Phase II Study to Evaluate the Safety, Tolerability, and Efficacy of IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer","sponsor":"Zhejiang University","enrolled":64,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06770439/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"},{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"technology":[{"id":"adc","kind":"technology","name":"Antibody-drug conjugate (ADC)","route":"/technologies/adc/"},{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"drug":[{"id":"gemcitabine","kind":"drug","name":"Gemcitabine","route":"/drugs/gemcitabine/"},{"id":"ibi343","kind":"drug","name":"IBI343","route":"/drugs/ibi343/"},{"id":"nab-paclitaxel","kind":"drug","name":"Nab-paclitaxel","route":"/drugs/nab-paclitaxel/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}