{"entity":{"id":"nct06782412","kind":"trial","name":"Multicenter Validation Trial of [18F]AlF-FAPI-74 for PET Imaging of Cancer-associated Fibroblasts Through Fibroblast Activation Protein Inhibitors (FAPI) in Dif","aka":["FAPIDO"],"tldr":"A phase 2/3 trial in pancreatic cancer, run by KU Leuven, now recruiting.","summary":"Multicenter Validation Trial of [18F]AlF-FAPI-74 for PET Imaging of Cancer-associated Fibroblasts Through Fibroblast Activation Protein Inhibitors (FAPI) in Different Tumor Types is a phase 2/3, interventional study registered as NCT06782412 by KU Leuven, with a registry enrolment figure of 109 participants, started 2025-02-06 and due to reach its primary completion in 2027-12. Interventions recorded: [18F]AlF-FAPI-74 PET/CT. Conditions listed: Oesophageal Cancer; Gastric Cancer; Pancreatic Ductal Adenocarcinoma; FAP; Oncology; Oncologic Disorders. Primary outcome: Primary Objective OGA: demonstrate superiority of [18F]AlF-FAPI-74 PET/CT over [18F]FDG PET/CT.; Primary Objective PDAC: demonstrate superiority of [18F]AlF-FAPI-74 PET/CT over conventional imaging (CT or MRI) or [18F]FDG PET/CT (if available); Primary Objective Clinically Challenging Situation: dem. Pancreatic eligibility wording from the registry: \"New histologic or cytologic proven diagnosis of pancreatic ductal adenocarcinoma\". Sites: Belgium. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06782412","url":"https://clinicaltrials.gov/study/NCT06782412"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06782412","phase":"2/3","setting":"Multicenter Validation Trial of [18F]AlF-FAPI-74 for PET Imaging of Cancer-associated Fibroblasts Through Fibroblast Activation Protein Inhibitors (FAPI) in Different Tumor Types","sponsor":"KU Leuven","enrolled":109,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06782412/","neighbours":{"cancer":[{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}