{"entity":{"id":"nct06791512","kind":"trial","name":"mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC","aka":["BASKETIII"],"tldr":"A phase 3 trial of fOLFOX (5-FU, leucovorin, oxaliplatin) in colorectal cancer, run by Jun Huang, now recruiting.","summary":"mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC is a phase 3, randomised interventional study registered as NCT06791512 by Jun Huang, with a registry enrolment figure of 166 participants, started 2025-01-18 and due to reach its primary completion in 2030-12-31. Interventions recorded: mFOLFOX6 + Bevacizumab + PD-1 monoclonal antibody; mFOLFOX6. Conditions listed: Colorectal Cancer (CRC); pMMR/MSS Adenocarcinoma of the Colon or Rectum. Primary outcome: 3 years DFS Rate. Colorectal eligibility wording from the registry: \"Histologically confirmed adenocarcinoma of the colon or upper rectum\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06791512","url":"https://clinicaltrials.gov/study/NCT06791512"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["cytotoxic-chemotherapy","platinum"],"targets":[],"drugs":["folfox"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06791512","phase":"3","setting":"mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Versus mFOLFOX6 as Neoadjuvant Therapy for Locally Advanced pMMR/MSS Colorectal Cancer: A Prospective, Multicenter, Randomized Phase III Study (BASKETIII)","sponsor":"Jun Huang","enrolled":166,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06791512/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"},{"id":"platinum","kind":"technology","name":"Platinum agents","route":"/technologies/platinum/"}],"drug":[{"id":"folfox","kind":"drug","name":"FOLFOX (5-FU, leucovorin, oxaliplatin)","route":"/drugs/folfox/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}