{"entity":{"id":"nct06793137","kind":"trial","name":"Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by AC Camargo Cancer Center, now recruiting.","summary":"Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer is a phase 2, interventional study registered as NCT06793137 by AC Camargo Cancer Center, with a registry enrolment figure of 100 participants, started 2024-07-22 and due to reach its primary completion in 2025-10-31. Interventions recorded: Metronidazole. Conditions listed: Rectal Cancer, Adenocarcinoma. Primary outcome: Complete clinical response in total neoadjuvant treatment of rectal adenocarcinoma. Colorectal eligibility wording from the registry: \"* Patients over 18 years old with middle and lower rectal adenocarcinoma, classified as locally advanced or where the tumor´s location necessitates rectal amputation surgery;\". Sites: Brazil. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06793137","url":"https://clinicaltrials.gov/study/NCT06793137"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06793137","phase":"2","setting":"Phase II Trial for Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer","sponsor":"AC Camargo Cancer Center","enrolled":100,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06793137/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}