{"entity":{"id":"nct06794086","kind":"trial","name":"SBRT + PD-1 Monoclonal Antibody in Unresectable Colorectal Liver Metastases","aka":["SPARKLE-L"],"tldr":"A phase 3 trial in colorectal cancer, run by Jun Huang, now recruiting.","summary":"SBRT + PD-1 Monoclonal Antibody in Unresectable Colorectal Liver Metastases is a phase 3, interventional study registered as NCT06794086 by Jun Huang, with a registry enrolment figure of 24 participants, started 2025-04-10 and due to reach its primary completion in 2026-06-20. Interventions recorded: Stereotactic body radiation therapy; PD-1 Monoclonal Antibody; Chemotherapy. Conditions listed: Colorectal Cancer; Liver Metastases. Primary outcome: ORR. Colorectal eligibility wording from the registry: \"Patients with pMMR/MSS colorectal adenocarcinoma;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06794086","url":"https://clinicaltrials.gov/study/NCT06794086"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["sbrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06794086","phase":"3","setting":"SBRT Combined With PD-1 Monoclonal Antibody in Unresectable Colorectal Liver Metastases: A Prospective, Multicenter, Single-arm, Phase II Clinical Study (SPARKLE-L)","sponsor":"Jun Huang","enrolled":24,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06794086/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}