{"entity":{"id":"nct06826092","kind":"trial","name":"Metformin for the Treatment of mCRC Patients Undergoing FOLFIRI Plus Target Therapy","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Kaohsiung Medical University Chung-Ho Memorial Hospital, now recruiting.","summary":"Metformin for the Treatment of mCRC Patients Undergoing FOLFIRI Plus Target Therapy is a phase 2, randomised interventional study registered as NCT06826092 by Kaohsiung Medical University Chung-Ho Memorial Hospital, with a registry enrolment figure of 110 participants, started 2022-10-31 and due to reach its primary completion in 2025-12-31. Interventions recorded: Metformin Pill; FOLFIRI plus target therapy only. Conditions listed: Progression-Free Survival. Primary outcome: Disease progression-free survival (PFS). Colorectal eligibility wording from the registry: \"Patients diagnosed with metastatic colorectal cancer who is going to receive FOLFIRI chemotherapy\". Sites: Taiwan. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06826092","url":"https://clinicaltrials.gov/study/NCT06826092"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06826092","phase":"2","setting":"Metformin as an Adjunctive Therapy for the Treatment of Metastatic Colorectal Cancer Patients Undergoing FOLFIRI Plus Target Therapy","sponsor":"Kaohsiung Medical University Chung-Ho Memorial Hospital","enrolled":110,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06826092/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}