{"entity":{"id":"nct06828757","kind":"trial","name":"Clinical Study of Nanocrystalline Megestrol in Malnourished Patients With First-Line Non-Small Cell Lung Cancer","aka":[],"tldr":"A phase 3 trial in lung cancer, run by Hunan Province Tumor Hospital, not yet recruiting.","summary":"Clinical Study of Nanocrystalline Megestrol in Malnourished Patients With First-Line Non-Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT06828757 by Hunan Province Tumor Hospital, with a registry enrolment figure of 94 participants, started 2025-05-01 and due to reach its primary completion in 2026-12-31. Interventions recorded: nanocrystalline megestrol oral suspension + PD-1/L1 inhibitor combined with chemotherapy; PD-1/L1 inhibitor combined with chemotherapy. Conditions listed: Non Small Cell Lung Cancer. Primary outcome: Appetite improvement level; Weight improvement level. Lung eligibility wording from the registry: \"(5) According to the 8th edition of the TNM stage classification of lung cancer with histological or cytologic evidence that cannot undergo complete surgical resection and cannot undergo radical synchronous/sequential chemoradiation and treatment ( IIIB/IIIC phase), metastatic (IV phase) NSCLC\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT06828757","url":"https://clinicaltrials.gov/study/NCT06828757"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06828757","phase":"3","setting":"A Phase III Prospective, Randomized, Parallel-Controlled Clinical Study of Nanocrystalline Megestrol in Malnourished Patients With First-Line Non-Small Cell Lung Cancer","sponsor":"Hunan Province Tumor Hospital","enrolled":94,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06828757/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}