{"entity":{"id":"nct06830239","kind":"trial","name":"Phase II Study of Neoadjuvant Dostarlimab in Patients With Untreated T3-4N0-2 or Stage III pMMR/MSS Resectable Colon Cancer","aka":["Superhero"],"tldr":"A phase 2 trial of dostarlimab in colorectal cancer, run by Universitaire Ziekenhuizen KU Leuven, now recruiting.","summary":"Phase II Study of Neoadjuvant Dostarlimab in Patients With Untreated T3-4N0-2 or Stage III pMMR/MSS Resectable Colon Cancer is a phase 2, interventional study registered as NCT06830239 by Universitaire Ziekenhuizen KU Leuven, with a registry enrolment figure of 10 participants, started 2025-04-03 and due to reach its primary completion in 2027-12. Interventions recorded: Dostarlimab. Conditions listed: Colon Cancer Stage III. Primary outcome: Multi-omic exploration. Colorectal eligibility wording from the registry: \"* primary adenocarcinoma colon cancer than can be removed surgically, staged cT3-4, cN0-2, cM0 or stage III\". Sites: Belgium. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06830239","url":"https://clinicaltrials.gov/study/NCT06830239"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":["checkpoint-inhibitor"],"targets":[],"drugs":["dostarlimab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06830239","phase":"2","setting":"Early Phase II Exploratory, Open-Label, Non-Randomized Study of Neoadjuvant Dostarlimab Monotherapy in Participants With Untreated T3-4N0-2 or Stage III pMMR/MSS Resectable Colon Cancer","sponsor":"Universitaire Ziekenhuizen KU Leuven","enrolled":10,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06830239/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"technology":[{"id":"checkpoint-inhibitor","kind":"technology","name":"Immune checkpoint inhibitors","route":"/technologies/checkpoint-inhibitor/"}],"drug":[{"id":"dostarlimab","kind":"drug","name":"Dostarlimab","route":"/drugs/dostarlimab/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}