{"entity":{"id":"nct06831955","kind":"trial","name":"LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer","aka":["LESLIE"],"tldr":"A phase 2 trial in triple-negative breast cancer, run by Universitaire Ziekenhuizen KU Leuven, now recruiting.","summary":"LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer is a phase 2, randomised interventional study registered as NCT06831955 by Universitaire Ziekenhuizen KU Leuven, with a registry enrolment figure of 356 participants, started 2026-02-01 and due to reach its primary completion in 2028-09-01. Interventions recorded: Exercise Therapy; Fasting-Mimicking Diet; SOC. Conditions listed: Triple Negative Breast Cancer (TNBC), Early Setting. Triple-negative eligibility wording from the registry: \"* The patient has a biopsy-confirmed diagnosis of stage II-III TNBC\". Sites: Belgium. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06831955","url":"https://clinicaltrials.gov/study/NCT06831955"}],"tags":["ctgov-ingest","tnbc-deep-dive"],"related":[],"cancers":["tnbc-early"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06831955","phase":"2","setting":"The LESLIE Trial: LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Systemic Therapy in Patients With Triple Negative Breast Cancer","sponsor":"Universitaire Ziekenhuizen KU Leuven","enrolled":356,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06831955/","neighbours":{"cancer":[{"id":"tnbc-early","kind":"cancer","name":"Early triple-negative breast cancer","route":"/cancers/tnbc-early/"}],"term":[{"id":"tnbc-trials-open-today","kind":"term","name":"Triple-negative breast cancer trials open today (registry snapshot and UK sites)","route":"/terms/tnbc-trials-open-today/"}]}}