{"entity":{"id":"nct06861452","kind":"trial","name":"Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma","aka":["SNIPER"],"tldr":"A phase 1/2 trial in pancreatic cancer, run by EIR Biotherapies s.r.l., now recruiting.","summary":"Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma is a phase 1/2, interventional study registered as NCT06861452 by EIR Biotherapies s.r.l., with a registry enrolment figure of 9 participants, started 2025-06-25 and due to reach its primary completion in 2027-07-29. Interventions recorded: RR001. Conditions listed: Locally Advanced Pancreatic Adenocarcinoma. Primary outcome: Evaluation of Safety in terms of monitoring of systemic tolerance, Adverse Events (AEs) and severe AEs (SAEs) assess by CTCAE (Version 5.0). Pancreatic eligibility wording from the registry: \"* Patients with confirmed pancreatic ductal adenocarcinoma classified as locally advanced pancreatic adenocarcinoma (LPAC)\". Sites: Italy. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06861452","url":"https://clinicaltrials.gov/study/NCT06861452"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06861452","phase":"1/2","setting":"RR001 in Combination With Chemotherapy for Patients With Locally Advanced Pancreatic Adenocarcinoma: Open-label, Non-randomized Dose Escalation Phase I/IIa Study","sponsor":"EIR Biotherapies s.r.l.","enrolled":9,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06861452/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}