{"entity":{"id":"nct06864013","kind":"trial","name":"SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by First Affiliated Hospital of Zhejiang University, now recruiting.","summary":"SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Cancer is a phase 2, randomised interventional study registered as NCT06864013 by First Affiliated Hospital of Zhejiang University, with a registry enrolment figure of 116 participants, started 2025-01-06 and due to reach its primary completion in 2029-12-31. Interventions recorded: Experimental; Control. Conditions listed: Locally Advanced Rectal Cancer (LARC). Primary outcome: Complete Response; Clinical Complete Response; Pathologic Complete Response. Colorectal eligibility wording from the registry: \"Histologically confirmed rectal adenocarcinoma\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06864013","url":"https://clinicaltrials.gov/study/NCT06864013"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06864013","phase":"2","setting":"Short-course Neoadjuvant Radiotherapy Combined With Chemotherapy and Iparomlimab and Tuvonralimab in Microsatellite Stability (MSS) or Mismatch-repair-proficient (pMMR) Patients With Locally Advanced Rectal Cancer: A Randomized Controlled Clinical Study","sponsor":"First Affiliated Hospital of Zhejiang University","enrolled":116,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06864013/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}