{"entity":{"id":"nct06866977","kind":"trial","name":"A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Advanced Pancreatic Cancer","aka":[],"tldr":"A phase 1/2 trial in pancreatic cancer, run by Xiangya Hospital of Central South University, not yet recruiting.","summary":"A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Advanced Pancreatic Cancer is a phase 1/2, interventional study registered as NCT06866977 by Xiangya Hospital of Central South University, with a registry enrolment figure of 10 participants, started 2025-03-12 and due to reach its primary completion in 2025-10-31. Interventions recorded: Oncolytic virus VRT106; Chemotherapy. Conditions listed: Pancreatic Cancer. Primary outcome: Safety and tolerability. Pancreatic eligibility wording from the registry: \"* Have unresectable pancreatic cancer as determined by imaging or surgical exploration and locally advanced or metastatic pancreatic ductal adenocarcinoma (including adenosquamous carcinoma) as confirmed by histology or cytology\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06866977","url":"https://clinicaltrials.gov/study/NCT06866977"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac","metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06866977","phase":"1/2","setting":"A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Advanced Pancreatic Cancer","sponsor":"Xiangya Hospital of Central South University","enrolled":10,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06866977/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"},{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}