{"entity":{"id":"nct06938282","kind":"trial","name":"An Exploratory Clinical Study of HRS-4642 in Combination With Immunotherapy and Chemotherapy for Pancreatic Cancer","aka":[],"tldr":"A phase 2 trial in pancreatic cancer, run by Shanghai Zhongshan Hospital, now recruiting.","summary":"An Exploratory Clinical Study of HRS-4642 in Combination With Immunotherapy and Chemotherapy for Pancreatic Cancer is a phase 2, interventional study registered as NCT06938282 by Shanghai Zhongshan Hospital, with a registry enrolment figure of 60 participants, started 2025-06-23 and due to reach its primary completion in 2027-04-30. Interventions recorded: HRS-4642. Conditions listed: Pancreatic Cancer. Primary outcome: Adverse events (AEs); Arm 1:Objective Response Rate (ORR); Arm 2:18m-OS rate. Pancreatic eligibility wording from the registry: \"Pathologically or cytologically confirmed ductal adenocarcinoma of the pancreas; and subjects must have at least one measurable lesion as defined by RECIST v1\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06938282","url":"https://clinicaltrials.gov/study/NCT06938282"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06938282","phase":"2","setting":"An Exploratory Clinical Study of HRS-4642 in Combination With Immunotherapy and Chemotherapy for Pancreatic Cancer","sponsor":"Shanghai Zhongshan Hospital","enrolled":60,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06938282/","neighbours":{"cancer":[{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}