{"entity":{"id":"nct06938867","kind":"trial","name":"Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant","aka":[],"tldr":"A phase 1/2 trial of SNIPR001 consists of genetically modified bacteriophages specifically targeting Escherichia coli in advanced solid tumours, run by SNIPR Biome Aps., now recruiting.","summary":"Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant is a phase 1/2 interventional study registered as NCT06938867 by SNIPR Biome Aps., with 24 participants planned, started 2025-02-25 and due to reach its primary completion in 2026-04-01. Interventions recorded: SNIPR001 consists of genetically modified bacteriophages specifically targeting Escherichia coli.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06938867","url":"https://clinicaltrials.gov/study/NCT06938867"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT06938867","phase":"1/2","setting":"A Phase 1b/2a, Randomized, Double-blind Study to Investigate Safety, Tolerability, PK, PD, and Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplantation Receiving Fluoroquinolone Prophylaxis and Harboring Fluoroquinolone-Resistant Escherichia Coli Pre-Transplant","sponsor":"SNIPR Biome Aps.","enrolled":24,"outcomes":[]},"route":"/trials/nct06938867/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}]}}