{"entity":{"id":"nct06943521","kind":"trial","name":"A Study of MT-4561 in Patients With Various Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of MT-4561 in head and neck squamous cell carcinoma, non-small-cell lung cancer, oesophageal cancer, gastric & gastro-oesophageal junction cancer, biliary tract cancer and pancreatic ductal adenocarcinoma, run by Tanabe Pharma America, Inc., now recruiting.","summary":"A Study of MT-4561 in Patients With Various Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06943521 by Tanabe Pharma America, Inc., with 27 participants planned, started 2025-04-18 and due to reach its primary completion in 2028-08. Interventions recorded: MT-4561.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06943521","url":"https://clinicaltrials.gov/study/NCT06943521"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["head-and-neck","nsclc","esophageal","gastric","cholangiocarcinoma","pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT06943521","phase":"1/2","setting":"A Phase I/II, Dose-escalation and Dose-optimization Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of MT-4561 in Patients With Various Advanced Solid Tumors and to Evaluate Effect of MT-4561 on Pharmacokinetics of Oral Midazolam","sponsor":"Tanabe Pharma America, Inc.","enrolled":27,"outcomes":[]},"route":"/trials/nct06943521/","neighbours":{"cancer":[{"id":"cholangiocarcinoma","kind":"cancer","name":"Biliary tract cancer (cholangiocarcinoma)","route":"/cancers/cholangiocarcinoma/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"esophageal","kind":"cancer","name":"Oesophageal cancer","route":"/cancers/esophageal/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}]}}