{"entity":{"id":"nct06974110","kind":"trial","name":"Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors","aka":[],"tldr":"A phase 1 trial of MOMA-341 run by MOMA Therapeutics, now recruiting.","summary":"Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors is a phase 1 interventional study registered as NCT06974110 by MOMA Therapeutics, with 132 participants planned, started 2025-07-16. Conditions recorded: Advanced Solid Tumor, Metastatic Solid Tumor, Endometrial Cancer, MSI-H Cancer, Colorectal Cancer, Gastric Cancer and dMMR Cancer. Interventions recorded: MOMA-341, Irinotecan and Immunotherapy.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT06974110","url":"https://clinicaltrials.gov/study/NCT06974110"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","endometrial","colorectal","gastric"],"sections":[],"technologies":[],"targets":[],"drugs":["moma-341"],"companies":["moma-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06974110","phase":"1","setting":"A Phase 1 Study of MOMA-341 as Monotherapy or Combination Therapy in Participants With Advanced or Metastatic Solid Tumors","sponsor":"MOMA Therapeutics","enrolled":132,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06974110/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"drug":[{"id":"moma-341","kind":"drug","name":"MOMA-341","route":"/drugs/moma-341/"}],"company":[{"id":"moma-therapeutics","kind":"company","name":"MOMA Therapeutics","route":"/companies/moma-therapeutics/"}]}}