{"entity":{"id":"nct06975293","kind":"trial","name":"STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas","aka":[],"tldr":"A phase 1/2 trial of Toripalimab in sarcomas and uterine sarcoma, run by STORM Therapeutics LTD, now recruiting.","summary":"STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas is a phase 1/2 interventional study registered as NCT06975293 by STORM Therapeutics LTD, with 107 participants planned, started 2025-05-05 and due to reach its primary completion in 2027-12-29. Interventions recorded: STC-15 in combination with toripalimab and STC-15 monotherapy.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06975293","url":"https://clinicaltrials.gov/study/NCT06975293"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["sarcoma","uterine-sarcoma"],"sections":[],"technologies":[],"targets":[],"drugs":["toripalimab"],"companies":["coherus"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT06975293","phase":"1/2","setting":"Open-label, Non-randomized, Multi-cohort, Phase 1b/2 Trial Investigating the Safety, Tolerability, and Antitumor Activity of STC-15 (a METTL3 Inhibitor) as a Part of Combination Therapy With Toripalimab in Participants With Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas","sponsor":"STORM Therapeutics LTD","enrolled":107,"outcomes":[]},"route":"/trials/nct06975293/","neighbours":{"cancer":[{"id":"sarcoma","kind":"cancer","name":"Sarcomas (soft tissue, bone, GIST)","route":"/cancers/sarcoma/"},{"id":"uterine-sarcoma","kind":"cancer","name":"Uterine sarcoma","route":"/cancers/uterine-sarcoma/"}],"drug":[{"id":"toripalimab","kind":"drug","name":"Toripalimab","route":"/drugs/toripalimab/"}],"company":[{"id":"coherus","kind":"company","name":"Coherus BioSciences","route":"/companies/coherus/"}]}}