{"entity":{"id":"nct07029399","kind":"trial","name":"A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors","aka":[],"tldr":"A phase 1 trial of NKT5097 run by NiKang Therapeutics, Inc., now recruiting.","summary":"A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors is a phase 1 interventional study registered as NCT07029399 by NiKang Therapeutics, Inc., with 361 participants planned, started 2025-03-25, primary completion expected 2027-07-31. Conditions recorded: HR+ Breast Cancer, Triple Negative Breast Cancer (TNBC), CCNE1 Amplified Advanced Solid Tumors, HR+ HER2- Breast Cancer. Interventions recorded: NKT5097 CDK2/CDK4 dual degrader, Fulvestrant, Letrozole.","status":"recruiting","asOf":"2026-11-04","links":[{"label":"ClinicalTrials.gov NCT07029399","url":"https://clinicaltrials.gov/study/NCT07029399"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["breast-hr-positive","tnbc"],"sections":[],"technologies":[],"targets":[],"drugs":["nkt5097"],"companies":["nikang-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07029399","phase":"1","setting":"A Phase 1, First-in-Human, Open-Label Study to Evaluate the Safety, Tolerability, PK, and Preliminary Anti-tumor Activity of the Novel Oral Selective CDK2/CDK4 Dual Degrader NKT5097 in Adults With Advanced/Metastatic Solid Tumors","sponsor":"NiKang Therapeutics, Inc.","enrolled":361,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07029399/","neighbours":{"cancer":[{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"drug":[{"id":"nkt5097","kind":"drug","name":"NKT5097","route":"/drugs/nkt5097/"}],"company":[{"id":"nikang-therapeutics","kind":"company","name":"NiKang Therapeutics","route":"/companies/nikang-therapeutics/"}]}}