{"entity":{"id":"nct07047560","kind":"trial","name":"Liposomal Irinotecan (II) Fractionated Dosing Combined With 5-FU/LV (FOLFIRInali-3) and Bevacizumab in Second-line Treatment of Advanced Colorectal Cancer: A Si","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Tianjin Medical University Cancer Institute and Hospital, now recruiting.","summary":"Liposomal Irinotecan (II) Fractionated Dosing Combined With 5-FU/LV (FOLFIRInali-3) and Bevacizumab in Second-line Treatment of Advanced Colorectal Cancer: A Single-arm, Phase II Clinical Study is a phase 2, interventional study registered as NCT07047560 by Tianjin Medical University Cancer Institute and Hospital, with a registry enrolment figure of 46 participants, started 2024-09-01 and due to reach its primary completion in 2026-08-01. Interventions recorded: fractionated liposomal irinotecan (II)-based combination chemotherapy (FOLFIRInali-3) plus bevacizumab (Bev). Conditions listed: Colorectal Cancer (CRC). Primary outcome: Objective Response Rate,ORR. Colorectal eligibility wording from the registry: \"Patients with pathologically confirmed advanced colorectal carcinoma (all other histological types excluded);\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07047560","url":"https://clinicaltrials.gov/study/NCT07047560"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07047560","phase":"2","setting":"Liposomal Irinotecan (II) Fractionated Dosing Combined With 5-FU/LV (FOLFIRInali-3) and Bevacizumab in Second-line Treatment of Advanced Colorectal Cancer: A Single-arm, Phase II Clinical Study","sponsor":"Tianjin Medical University Cancer Institute and Hospital","enrolled":46,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07047560/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}