{"entity":{"id":"nct07059949","kind":"trial","name":"Short Course Radiotherapy Followed by CAPOX and Carrilizumab and Bevacizumab or Cetuximab for the Initial Treatment of Unresectable Metastatic Rectal Cancer","aka":["Union-mRC"],"tldr":"A phase 2 trial in colorectal cancer, run by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, not yet recruiting.","summary":"Short Course Radiotherapy Followed by CAPOX and Carrilizumab and Bevacizumab or Cetuximab for the Initial Treatment of Unresectable Metastatic Rectal Cancer is a phase 2, interventional study registered as NCT07059949 by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, with a registry enrolment figure of 80 participants, started 2025-06-30 and due to reach its primary completion in 2027-01-30. Interventions recorded: CAPOX+ Camrelizumab+ Cetuximab; CAPOX+ Camrelizumab+ Bevacizumab. Conditions listed: Unresectable Metastatic Rectal Cancer; CAPOX; Combination of Radioimmunotherapy. Primary outcome: ORR. Colorectal eligibility wording from the registry: \"Histologically confirmed rectal cancer with initial treatment (no surgery, radiotherapy, chemotherapy, targeted therapy or immunotherapy);\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07059949","url":"https://clinicaltrials.gov/study/NCT07059949"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07059949","phase":"2","setting":"Phase II, Single-center Study of Short-course Radiotherapy Followed by CAPOX and Carrelizumab and Bevacizumab or Cetuximab in the Treatment of Initially Unresectable Metastatic Rectal Cancer","sponsor":"Union Hospital, Tongji Medical College, Huazhong University of Science and Technology","enrolled":80,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07059949/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}