{"entity":{"id":"nct07076693","kind":"trial","name":"Standard-of-care Systemic Therapy With or Without Local Therapy in Patients With Oligoprogressive Non-Small Cell Lung Cancer(NSCLC）","aka":[],"tldr":"A phase 2/3 trial in lung cancer, run by Shanghai Chest Hospital, active but no longer recruiting.","summary":"Standard-of-care Systemic Therapy With or Without Local Therapy in Patients With Oligoprogressive Non-Small Cell Lung Cancer(NSCLC） is a phase 2/3, randomised interventional study registered as NCT07076693 by Shanghai Chest Hospital, with a registry enrolment figure of 97 participants, started 2025-06-03 and due to reach its primary completion in 2028-05-31. Interventions recorded: Radiotherapy or Surgery; Standard Medical Therapy. Conditions listed: OligoProgressive Metastatic Disease; Non-Small Cell Lung Cancer. Primary outcome: Objective Response Rate (ORR); Progression-free survival (PFS). Lung eligibility wording from the registry: \"For Epidermal Growth Factor Receptor (EGFR)-sensitive mutant non-squamous NSCLC patients, first-line treatment must be the third-generation TKIs or progression after first/second-generation TKI without harboring T790M mutation, with ≤3 progressive lesions and ≤3 metastatic organs (PET-CT + cranial M\". Sites: China. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT07076693","url":"https://clinicaltrials.gov/study/NCT07076693"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07076693","phase":"2/3","setting":"Standard-of-care Systemic Therapy With or Without Local Therapy in Patients With Oligoprogressive NSCLC: A Prospective, Randomized Controlled Phase II/III Clinical Trial","sponsor":"Shanghai Chest Hospital","enrolled":97,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07076693/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}