{"entity":{"id":"nct07102381","kind":"trial","name":"A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer","aka":[],"tldr":"A phase 2 trial of Zanidatamab, Paclitaxel / nab-paclitaxel, Docetaxel in her2-positive breast cancer, run by Jazz Pharmaceuticals, now recruiting.","summary":"A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer is a phase 2 interventional study registered as NCT07102381 by Jazz Pharmaceuticals, with 125 participants planned, started 2025-09-24 and due to reach its primary completion in 2028-01-01. Interventions recorded: Zanidatamab, Paclitaxel, Docetaxel, Carboplatin, Trastuzumab. Conditions listed: HER2-positive Breast Cancer, Breast Cancer. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07102381","url":"https://clinicaltrials.gov/study/NCT07102381"}],"tags":["ctgov-ingest"],"related":[],"cancers":["breast-her2-positive"],"sections":[],"technologies":[],"targets":[],"drugs":["zanidatamab","paclitaxel","docetaxel","carboplatin","trastuzumab","pertuzumab"],"companies":["jazz"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT07102381","phase":"2","setting":"A Phase 2, Randomized, Multicenter, Open-label Neoadjuvant Study Evaluating Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer","sponsor":"Jazz Pharmaceuticals","enrolled":125,"outcomes":[]},"route":"/trials/nct07102381/","neighbours":{"cancer":[{"id":"breast-her2-positive","kind":"cancer","name":"HER2-positive breast cancer","route":"/cancers/breast-her2-positive/"}],"drug":[{"id":"carboplatin","kind":"drug","name":"Carboplatin","route":"/drugs/carboplatin/"},{"id":"docetaxel","kind":"drug","name":"Docetaxel","route":"/drugs/docetaxel/"},{"id":"paclitaxel","kind":"drug","name":"Paclitaxel / nab-paclitaxel","route":"/drugs/paclitaxel/"},{"id":"pertuzumab","kind":"drug","name":"Pertuzumab","route":"/drugs/pertuzumab/"},{"id":"trastuzumab","kind":"drug","name":"Trastuzumab","route":"/drugs/trastuzumab/"},{"id":"zanidatamab","kind":"drug","name":"Zanidatamab","route":"/drugs/zanidatamab/"}],"company":[{"id":"jazz","kind":"company","name":"Jazz Pharmaceuticals","route":"/companies/jazz/"}]}}