{"entity":{"id":"nct07118800","kind":"trial","name":"Study Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old","aka":["NACRE-2"],"tldr":"A phase 3 trial in colorectal cancer, run by UNICANCER, not yet recruiting.","summary":"Study Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old is a phase 3, randomised interventional study registered as NCT07118800 by UNICANCER, with a registry enrolment figure of 160 participants, started 2026-07-24 and due to reach its primary completion in 2030-12-15. Interventions recorded: FOLFOX4s; Short Course Radiotherapy. Conditions listed: Locally Advanced Rectal Adenocarcinoma. Primary outcome: TME-free survival. Colorectal eligibility wording from the registry: \"Histologically confirmed diagnosis of adenocarcinoma of the rectum\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07118800","url":"https://clinicaltrials.gov/study/NCT07118800"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":["unicancer"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07118800","phase":"3","setting":"Randomized Phase III Study Evaluating Two Treatment Strategies for Locally Advanced Rectal Cancer in Patients ≥75 Years Old","sponsor":"UNICANCER","enrolled":160,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07118800/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"company":[{"id":"unicancer","kind":"company","name":"UNICANCER","route":"/companies/unicancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}