{"entity":{"id":"nct07123441","kind":"trial","name":"A Study on the Efficacy and Safety of Irinotecan Liposome (II), 5-FU/LV in Combination With Bevacizumab for the Treatment of Advanced Colorectal Cancer","aka":[],"tldr":"A phase 2 trial of leucovorin (folinic acid) in colorectal cancer, run by Sanjun Cai, not yet recruiting.","summary":"A Study on the Efficacy and Safety of Irinotecan Liposome (II), 5-FU/LV in Combination With Bevacizumab for the Treatment of Advanced Colorectal Cancer is a phase 2, interventional study registered as NCT07123441 by Sanjun Cai, with a registry enrolment figure of 300 participants, started 2025-09-01 and due to reach its primary completion in 2027-09-01. Interventions recorded: Bevacizumab,Irinotecan liposome (II),5-FU/LV. Conditions listed: Colorectal Cancer. Primary outcome: Safety:The incidence of adverse events. Colorectal eligibility wording from the registry: \"Patients with pathologically confirmed, unresectable advanced colorectal cancer;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07123441","url":"https://clinicaltrials.gov/study/NCT07123441"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":["leucovorin"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07123441","phase":"2","setting":"A Study on the Efficacy and Safety of Irinotecan Liposome (II), 5-FU/LV in Combination With Bevacizumab for the Treatment of Advanced Colorectal Cancer","sponsor":"Sanjun Cai","enrolled":300,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07123441/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"drug":[{"id":"leucovorin","kind":"drug","name":"Leucovorin (folinic acid)","route":"/drugs/leucovorin/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}