{"entity":{"id":"nct07124936","kind":"trial","name":"A Study of HDM2005 in Combination With Standard of Care in Patients With Diffuse Large B-Cell Lymphoma","aka":[],"tldr":"A phase 1/2 trial of Gemcitabine, CAPOX, Cyclophosphamide in diffuse large b-cell lymphoma, run by Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd., now recruiting.","summary":"A Study of HDM2005 in Combination With Standard of Care in Patients With Diffuse Large B-Cell Lymphoma is a phase 1/2 interventional study registered as NCT07124936 by Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd., with 97 participants planned, started 2025-07-30 and due to reach its primary completion in 2027-10-26. Interventions recorded: HDM2005, Rituximab or Rituximab biosimilar, Gemcitabine, Oxaliplatin, Cyclophosphamide. Conditions listed: Diffuse Large B Cell Lymphoma (DLBCL). No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07124936","url":"https://clinicaltrials.gov/study/NCT07124936"}],"tags":["ctgov-ingest"],"related":[],"cancers":["dlbcl"],"sections":[],"technologies":[],"targets":[],"drugs":["gemcitabine","capox","cyclophosphamide","doxorubicin","prednisone"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT07124936","phase":"1/2","setting":"A Phase 1b/2 Study to Evaluate the Safety, Tolerability, and Antitumor Activity of HDM2005 in Combination With Standard of Care in Patients With Diffuse Large B-Cell Lymphoma","sponsor":"Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.","enrolled":97,"outcomes":[]},"route":"/trials/nct07124936/","neighbours":{"cancer":[{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"}],"drug":[{"id":"capox","kind":"drug","name":"CAPOX (capecitabine, oxaliplatin)","route":"/drugs/capox/"},{"id":"cyclophosphamide","kind":"drug","name":"Cyclophosphamide","route":"/drugs/cyclophosphamide/"},{"id":"doxorubicin","kind":"drug","name":"Doxorubicin","route":"/drugs/doxorubicin/"},{"id":"gemcitabine","kind":"drug","name":"Gemcitabine","route":"/drugs/gemcitabine/"},{"id":"prednisone","kind":"drug","name":"Prednisone","route":"/drugs/prednisone/"}]}}