{"entity":{"id":"nct07156682","kind":"trial","name":"QL1706 Plus XELOX as Neoadjuvant Therapy for MSS/pMMR Clinical Stage III Colon Cancer","aka":[],"tldr":"A phase 2 trial of QL1706 and cAPOX (capecitabine, oxaliplatin) in colorectal cancer, run by Qilu Hospital of Shandong University, not yet recruiting.","summary":"QL1706 Plus XELOX as Neoadjuvant Therapy for MSS/pMMR Clinical Stage III Colon Cancer is a phase 2, interventional study registered as NCT07156682 by Qilu Hospital of Shandong University, with a registry enrolment figure of 21 participants, started 2025-09-25 and due to reach its primary completion in 2027-06-30. Interventions recorded: QL1706; XELOX. Conditions listed: Colon Cancer; MSS/pMMR; QL1706. Primary outcome: Pathological Complete Response (pCR). Colorectal eligibility wording from the registry: \"* Histologically or clinically confirmed initially resectable Stage III colon cancer according to the AJCC 8th edition\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07156682","url":"https://clinicaltrials.gov/study/NCT07156682"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":["cytotoxic-chemotherapy","platinum"],"targets":[],"drugs":["ql1706","capox"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07156682","phase":"2","setting":"A Single-Arm, Exploratory Study of Iparomlimab and Tuvonralimab (QL1706) Plus XELOX as Neoadjuvant Therapy in Patients With Microsatellite Stable (pMMR/MSS) Resectable Stage III Colon Cancer","sponsor":"Qilu Hospital of Shandong University","enrolled":21,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07156682/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"},{"id":"platinum","kind":"technology","name":"Platinum agents","route":"/technologies/platinum/"}],"drug":[{"id":"capox","kind":"drug","name":"CAPOX (capecitabine, oxaliplatin)","route":"/drugs/capox/"},{"id":"ql1706","kind":"drug","name":"QL1706","route":"/drugs/ql1706/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}