{"entity":{"id":"nct07169734","kind":"trial","name":"A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of ALE.P03 in non-small-cell lung cancer, colorectal cancer, biliary tract cancer and bladder & urothelial cancer, run by Alentis Therapeutics AG, now recruiting.","summary":"A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors is a phase 1/2 interventional study registered as NCT07169734 by Alentis Therapeutics AG, with 180 participants planned, started 2025-08-26 and due to reach its primary completion in 2029-04-05. Interventions recorded: ALE.P03.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07169734","url":"https://clinicaltrials.gov/study/NCT07169734"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["nsclc","colorectal","cholangiocarcinoma","urothelial"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["alentis-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT07169734","phase":"1/2","setting":"A Phase I/II, Open-label, Multicenter Study of ALE.P03 (Claudin-1 Targeted Antibody-drug Conjugate) as a Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors","sponsor":"Alentis Therapeutics AG","enrolled":180,"outcomes":[]},"route":"/trials/nct07169734/","neighbours":{"cancer":[{"id":"cholangiocarcinoma","kind":"cancer","name":"Biliary tract cancer (cholangiocarcinoma)","route":"/cancers/cholangiocarcinoma/"},{"id":"urothelial","kind":"cancer","name":"Bladder & urothelial cancer","route":"/cancers/urothelial/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"company":[{"id":"alentis-therapeutics","kind":"company","name":"Alentis Therapeutics","route":"/companies/alentis-therapeutics/"}]}}