{"entity":{"id":"nct07170644","kind":"trial","name":"A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)","aka":[],"tldr":"A phase 2 trial of Nirogacestat in desmoid tumour, run by SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany, active and no longer recruiting.","summary":"A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF) is a phase 2 interventional study registered as NCT07170644 by SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany, with 20 participants enrolled, started 2025-08-08 and due to reach its primary completion in 2027-05-28. Interventions recorded: Nirogacestat oral tablet. Conditions listed: Desmoid Tumor, Aggressive Fibromatosis. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07170644","url":"https://clinicaltrials.gov/study/NCT07170644"}],"tags":["ctgov-ingest"],"related":[],"cancers":["desmoid-tumour"],"sections":[],"technologies":[],"targets":[],"drugs":["nirogacestat"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT07170644","phase":"2","setting":"A Single-arm, Open-label Phase 2 Study of Nirogacestat in Adult Japanese Patients With Progressing Desmoid Tumors/Aggressive Fibromatosis (DT/AF)","sponsor":"SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany","enrolled":20,"outcomes":[]},"route":"/trials/nct07170644/","neighbours":{"cancer":[{"id":"desmoid-tumour","kind":"cancer","name":"Desmoid tumour","route":"/cancers/desmoid-tumour/"}],"drug":[{"id":"nirogacestat","kind":"drug","name":"Nirogacestat","route":"/drugs/nirogacestat/"}]}}