{"entity":{"id":"nct07175636","kind":"trial","name":"QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Sun Yat-sen University, not yet recruiting.","summary":"QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer is a phase 2, interventional study registered as NCT07175636 by Sun Yat-sen University, with a registry enrolment figure of 66 participants, started 2025-09-20 and due to reach its primary completion in 2026-09-20. Interventions recorded: Drug: QL1706 Drug: mFOLFOX6 Radiation: Short-Course Radiotherapy (SCRT). Conditions listed: Locally Advanced Rectal Cancer (LARC); Mismatch Repair-Proficient (pMMR) Rectal Cancer; Non-metastatic Rectal Cancer. Primary outcome: Pathologic Complete Response (pCR) Rate. Colorectal eligibility wording from the registry: \"Histologically confirmed rectal adenocarcinoma\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07175636","url":"https://clinicaltrials.gov/study/NCT07175636"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","msi-high-colorectal"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07175636","phase":"2","setting":"A Multicenter, Prospective, Phase II Clinical Trial of Short-Course Radiotherapy Followed by QL1706 Plus mFOLFOX6 as Total Neoadjuvant Therapy for Patients With pMMR/MSS Locally Advanced Rectal Cancer","sponsor":"Sun Yat-sen University","enrolled":66,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07175636/","neighbours":{"cancer":[{"id":"msi-high-colorectal","kind":"cancer","name":"Mismatch-repair deficient (MSI-high) colorectal cancer","route":"/cancers/msi-high-colorectal/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}