{"entity":{"id":"nct07182149","kind":"trial","name":"A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors","aka":[],"tldr":"A phase 1 trial of NRM-823 run by Normunity AccelCo, Inc., now recruiting.","summary":"A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors is a phase 1 interventional study registered as NCT07182149 by Normunity AccelCo, Inc., with 150 participants planned, started 2025-10-30. Conditions recorded: HNSCC, ESCC, Esophageal Adenocarcinoma, Gastric Adenocarcinoma, GEJ Adenocarcinoma, Ovarian Cancer, NSCLC, Cervical Cancer, Endometrial Cancer and Triple Negative Breast Cancer (TNBC). Interventions recorded: NRM-823.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07182149","url":"https://clinicaltrials.gov/study/NCT07182149"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["head-and-neck","oesophageal-squamous-cell-carcinoma","oesophageal-adenocarcinoma","gastric","ovarian","nsclc","cervical","endometrial","tnbc"],"sections":[],"technologies":[],"targets":[],"drugs":["nrm-823"],"companies":["normunity"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07182149","phase":"1","setting":"A Phase 1a/1b Study of NRM-823 as Monotherapy and in Combination With Immune Checkpoint Inhibition in Participants With Locally Advanced or Metastatic Refractory Solid Tumors","sponsor":"Normunity AccelCo, Inc.","enrolled":150,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07182149/","neighbours":{"cancer":[{"id":"cervical","kind":"cancer","name":"Cervical cancer","route":"/cancers/cervical/"},{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"oesophageal-adenocarcinoma","kind":"cancer","name":"Oesophageal and junctional adenocarcinoma","route":"/cancers/oesophageal-adenocarcinoma/"},{"id":"oesophageal-squamous-cell-carcinoma","kind":"cancer","name":"Oesophageal squamous cell carcinoma","route":"/cancers/oesophageal-squamous-cell-carcinoma/"},{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"drug":[{"id":"nrm-823","kind":"drug","name":"NRM-823","route":"/drugs/nrm-823/"}],"company":[{"id":"normunity","kind":"company","name":"Normunity","route":"/companies/normunity/"}]}}