{"entity":{"id":"nct07197554","kind":"trial","name":"A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies","aka":[],"tldr":"A phase 1 trial of ST-01156 run by SEED Therapeutics, Inc., now recruiting.","summary":"A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies is a phase 1 interventional study registered as NCT07197554 by SEED Therapeutics, Inc., with 171 participants planned, started 2025-12-01. Conditions recorded: Advanced Solid Tumors, Ewing Sarcoma, Hepatocellular Carcinoma (HCC) and Biliary Tract Cancer (BTC). Interventions recorded: ST-01156.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07197554","url":"https://clinicaltrials.gov/study/NCT07197554"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","ewing-sarcoma","hcc","biliary-tract-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["st-01156"],"companies":["seed-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07197554","phase":"1","setting":"A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies","sponsor":"SEED Therapeutics, Inc.","enrolled":171,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07197554/","neighbours":{"cancer":[{"id":"biliary-tract-cancer","kind":"cancer","name":"Biliary tract cancer (all types)","route":"/cancers/biliary-tract-cancer/"},{"id":"ewing-sarcoma","kind":"cancer","name":"Ewing sarcoma","route":"/cancers/ewing-sarcoma/"},{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"drug":[{"id":"st-01156","kind":"drug","name":"ST-01156","route":"/drugs/st-01156/"}],"company":[{"id":"seed-therapeutics","kind":"company","name":"SEED Therapeutics","route":"/companies/seed-therapeutics/"}]}}