{"entity":{"id":"nct07200141","kind":"trial","name":"Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer","aka":["SIB-NCRT"],"tldr":"A phase 2 trial in colorectal cancer, run by Peking Union Medical College Hospital, now recruiting.","summary":"Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer is a phase 2, randomised interventional study registered as NCT07200141 by Peking Union Medical College Hospital, with a registry enrolment figure of 156 participants, started 2025-10-01 and due to reach its primary completion in 2026-12-01. Interventions recorded: GTV 58.75 Gy/25 fractions(Simultaneous Integrated Boost); GTV 50 Gy/25 fractions(Simultaneous Integrated Boost); Concurrent Chemotherapy; Total mesorectal excision (TME) surgery or non-operative management. Conditions listed: Locally Advanced Rectal Adenocarcinoma. Primary outcome: CR. Colorectal eligibility wording from the registry: \"Histologically confirmed rectal adenocarcinoma\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07200141","url":"https://clinicaltrials.gov/study/NCT07200141"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07200141","phase":"2","setting":"Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer：A Phase 2, Randomized Controlled Study","sponsor":"Peking Union Medical College Hospital","enrolled":156,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07200141/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}