{"entity":{"id":"nct07213882","kind":"trial","name":"A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL)","aka":[],"tldr":"A phase 1 trial of DT-7012 run by Assistance Publique - Hôpitaux de Paris, not yet recruiting.","summary":"A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL) is a phase 1 interventional study registered as NCT07213882 by Assistance Publique - Hôpitaux de Paris, with 30 participants planned, started 2026-01-01. Conditions recorded: Cutaneous T Cell Lymphoma (CTCL), Mycosis Fungoides and Sezary Syndrome. Interventions recorded: DT-7012.","status":"planned","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT07213882","url":"https://clinicaltrials.gov/study/NCT07213882"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["non-hodgkin-lymphoma","mycosis-fungoides","cutaneous-t-cell-lymphoma"],"sections":[],"technologies":[],"targets":[],"drugs":["dt-7012"],"companies":["domain-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07213882","phase":"1","setting":"A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL)","sponsor":"Assistance Publique - Hôpitaux de Paris","enrolled":30,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07213882/","neighbours":{"cancer":[{"id":"cutaneous-t-cell-lymphoma","kind":"cancer","name":"Cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)","route":"/cancers/cutaneous-t-cell-lymphoma/"},{"id":"mycosis-fungoides","kind":"cancer","name":"Mycosis fungoides","route":"/cancers/mycosis-fungoides/"},{"id":"non-hodgkin-lymphoma","kind":"cancer","name":"Non-Hodgkin lymphoma (all types)","route":"/cancers/non-hodgkin-lymphoma/"}],"drug":[{"id":"dt-7012","kind":"drug","name":"DT-7012","route":"/drugs/dt-7012/"}],"company":[{"id":"domain-therapeutics","kind":"company","name":"Kainova Therapeutics","route":"/companies/domain-therapeutics/"}]}}