{"entity":{"id":"nct07214142","kind":"trial","name":"Total Neoadjuvant Therapy With PD-1 for Locally Advcancer Rectal Cancer","aka":["TNT-Immunity"],"tldr":"A phase 2 trial in colorectal cancer, run by The First Affiliated Hospital of University of Science and Technology of China, not yet recruiting.","summary":"Total Neoadjuvant Therapy With PD-1 for Locally Advcancer Rectal Cancer is a phase 2, interventional study registered as NCT07214142 by The First Affiliated Hospital of University of Science and Technology of China, with a registry enrolment figure of 30 participants, started 2025-10-01 and due to reach its primary completion in 2027-12-31. Interventions recorded: PD-1. Conditions listed: Rectal Cancer Patients. Primary outcome: pathological complete response rate. Colorectal eligibility wording from the registry: \"Pathologically confirmed rectal adenocarcinoma;\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07214142","url":"https://clinicaltrials.gov/study/NCT07214142"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07214142","phase":"2","setting":"Efficacy and Safety of Total Neoadjuvant Chemoradiotherapy Combined With PD-1 Therapy for Locally Advanced Rectal Cancer With High Risk of Recurrence","sponsor":"The First Affiliated Hospital of University of Science and Technology of China","enrolled":30,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07214142/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}