{"entity":{"id":"nct07224022","kind":"trial","name":"Cemiplimab With Fianlimab for Resectable Non-Metastatic Colon Cancer","aka":["NACho"],"tldr":"A phase 2 trial of cemiplimab in colorectal cancer, run by John Strickler, M.D., not yet recruiting.","summary":"Cemiplimab With Fianlimab for Resectable Non-Metastatic Colon Cancer is a phase 2, interventional study registered as NCT07224022 by John Strickler, M.D., with a registry enrolment figure of 24 participants, started 2026-10-01 and due to reach its primary completion in 2028-12-31. Interventions recorded: Cemiplimab + Fianlimab [Fixed Dose Combination (FDC)]. Conditions listed: Colon Cancer. Primary outcome: Feasibility of treatment with cemiplimab and fianlimab before surgery; Safety of treatment with cemiplimab and fianlimab before surgery. Colorectal eligibility wording from the registry: \"Histologically and/or cytologically documented adenocarcinoma of the colon\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07224022","url":"https://clinicaltrials.gov/study/NCT07224022"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":["checkpoint-inhibitor"],"targets":[],"drugs":["cemiplimab"],"companies":["regeneron"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07224022","phase":"2","setting":"NACho: A Study of Neo-Adjuvant Cemiplimab With Fianlimab for Resectable Non-Metastatic Colon Cancer","sponsor":"John Strickler, M.D.","enrolled":24,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07224022/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"technology":[{"id":"checkpoint-inhibitor","kind":"technology","name":"Immune checkpoint inhibitors","route":"/technologies/checkpoint-inhibitor/"}],"drug":[{"id":"cemiplimab","kind":"drug","name":"Cemiplimab","route":"/drugs/cemiplimab/"}],"company":[{"id":"regeneron","kind":"company","name":"Regeneron","route":"/companies/regeneron/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}