{"entity":{"id":"nct07246863","kind":"trial","name":"Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC","aka":[],"tldr":"A phase 2 trial of Visugromab, Nivolumab, Docetaxel in non-small-cell lung cancer and small-cell lung cancer, run by CatalYm GmbH, now recruiting.","summary":"Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC is a phase 2 interventional study registered as NCT07246863 by CatalYm GmbH, with 131 participants planned, started 2025-10-07 and due to reach its primary completion in 2029-10-01. Interventions recorded: Visugromab RDE (recommended dose for expansion), Visugromab 6mg/kg, Nivolumab, Placebo Saline Infusion, Docetaxel. Conditions listed: Metastatic Non-Squamous Non-Small Cell Lung Cancer, Adult Solid Tumor. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07246863","url":"https://clinicaltrials.gov/study/NCT07246863"}],"tags":["ctgov-ingest"],"related":[],"cancers":["nsclc","sclc"],"sections":[],"technologies":[],"targets":[],"drugs":["visugromab","nivolumab","docetaxel"],"companies":["catalym"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT07246863","phase":"2","setting":"Ph 2, Randomized, Blinded, Placebo-Controlled Trial Investigating the Efficacy and Safety of Visugromab and Nivolumab With or Without Docetaxel Versus Docetaxel in 2L Treatment of Participants With Metastatic NSCLC (GDFATHER-NSCLC-02)","sponsor":"CatalYm GmbH","enrolled":131,"outcomes":[]},"route":"/trials/nct07246863/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"drug":[{"id":"docetaxel","kind":"drug","name":"Docetaxel","route":"/drugs/docetaxel/"},{"id":"nivolumab","kind":"drug","name":"Nivolumab","route":"/drugs/nivolumab/"},{"id":"visugromab","kind":"drug","name":"Visugromab","route":"/drugs/visugromab/"}],"company":[{"id":"catalym","kind":"company","name":"CatalYm","route":"/companies/catalym/"}]}}