{"entity":{"id":"nct07253896","kind":"trial","name":"Efficacy and Safety of AK104 Combined With Chemotherapy and Cetuximab or Bevacizumab","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Second Affiliated Hospital, Zhejiang University, School of Medicine, now recruiting.","summary":"Efficacy and Safety of AK104 Combined With Chemotherapy and Cetuximab or Bevacizumab is a phase 2, interventional study registered as NCT07253896 by Second Affiliated Hospital, Zhejiang University, School of Medicine, with a registry enrolment figure of 40 participants, started 2024-01-03 and due to reach its primary completion in 2026-01-03. Interventions recorded: AK104 and cetuximab or bevacizumab and FOLFIRI. Conditions listed: Safety. Primary outcome: objective response rate. Colorectal eligibility wording from the registry: \"Metastatic colorectal adenocarcinoma confirmed by histology or cytology\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07253896","url":"https://clinicaltrials.gov/study/NCT07253896"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07253896","phase":"2","setting":"Efficacy and Safety of AK104 Combined With Chemotherapy and Cetuximab or Bevacizumab as Second-line Treatment in MSS Type Metastatic Colorectal Cancer Based on RAS Gene Status","sponsor":"Second Affiliated Hospital, Zhejiang University, School of Medicine","enrolled":40,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07253896/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}