{"entity":{"id":"nct07276880","kind":"trial","name":"Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer","aka":["P-RAD(+)TN-DCT"],"tldr":"A phase 2 trial in triple-negative breast cancer, run by UNC Lineberger Comprehensive Cancer Center, now recruiting.","summary":"Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer is a phase 2, randomised interventional study registered as NCT07276880 by UNC Lineberger Comprehensive Cancer Center, with a registry enrolment figure of 32 participants, started 2026-03-17 and due to reach its primary completion in 2027-11. Interventions recorded: Neoadjuvant Pembrolizumab; low dose neoadjuvant boost; High dose neoadjuvant boost. Conditions listed: Breast Cancer; Triple Negative Breast Cancer (TNBC); HER2-Negative Breast Carcinoma; Node-positive Breast Cancer. Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07276880","url":"https://clinicaltrials.gov/study/NCT07276880"}],"tags":["ctgov-ingest","tnbc-deep-dive"],"related":[],"cancers":["tnbc-early"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07276880","phase":"2","setting":"Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer","sponsor":"UNC Lineberger Comprehensive Cancer Center","enrolled":32,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07276880/","neighbours":{"cancer":[{"id":"tnbc-early","kind":"cancer","name":"Early triple-negative breast cancer","route":"/cancers/tnbc-early/"}],"term":[{"id":"tnbc-trials-open-today","kind":"term","name":"Triple-negative breast cancer trials open today (registry snapshot and UK sites)","route":"/terms/tnbc-trials-open-today/"}]}}