{"entity":{"id":"nct07281157","kind":"trial","name":"Liposomal Irinotecan, Capecitabine and Enlonstobart With Short-Course Radiotherapy for Locally Advanced Rectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Tianjin Medical University Cancer Institute and Hospital, now recruiting.","summary":"Liposomal Irinotecan, Capecitabine and Enlonstobart With Short-Course Radiotherapy for Locally Advanced Rectal Cancer is a phase 2, interventional study registered as NCT07281157 by Tianjin Medical University Cancer Institute and Hospital, with a registry enrolment figure of 30 participants, started 2025-11-01 and due to reach its primary completion in 2027-04-30. Interventions recorded: Irinotecan Liposome, Capecitabine, and Enlansubemab Plus Short-Course Radiotherapy. Conditions listed: Advanced Rectal Cancer. Primary outcome: Complete response plus pathological complete response. Colorectal eligibility wording from the registry: \"rectal adenocarcinoma confirmed by histology and/or cytology;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07281157","url":"https://clinicaltrials.gov/study/NCT07281157"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07281157","phase":"2","setting":"Liposomal Irinotecan, Capecitabine, and Enlonstobart Combined With Short-Course Radiotherapy as Neoadjuvant Therapy for Locally Advanced Rectal Cancer: A Prospective, Single-Center, Single-Arm Study","sponsor":"Tianjin Medical University Cancer Institute and Hospital","enrolled":30,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07281157/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}