{"entity":{"id":"nct07283198","kind":"trial","name":"A Phase II Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics/Pharmacodynamics of JSKN033 in Patients With Advanced Non-Small Cell Lung Cancer","aka":[],"tldr":"A phase 2 trial in lung cancer, run by Jiangsu Alphamab Biopharmaceuticals Co., Ltd, not yet recruiting.","summary":"A Phase II Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics/Pharmacodynamics of JSKN033 in Patients With Advanced Non-Small Cell Lung Cancer is a phase 2, interventional study registered as NCT07283198 by Jiangsu Alphamab Biopharmaceuticals Co., Ltd, with a registry enrolment figure of 160 participants, started 2025-12-10 and due to reach its primary completion in 2027-08-30. Interventions recorded: JSKN033 Injection. Conditions listed: Non Small Cell Lung Cancer (NSCLC). Primary outcome: Number and Severity of Treatment-emergent Adverse Events (TEAEs); Objective response rate (ORR). Lung eligibility wording from the registry: \"Histologically or cytologically confirmed locally advanced or metastatic NSCLC (per AJCC 8th Edition Lung Cancer TNM Staging) that is not eligible for curative surgery and/or curative radiotherapy\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT07283198","url":"https://clinicaltrials.gov/study/NCT07283198"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["alphamab"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07283198","phase":"2","setting":"A Phase II Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics/Pharmacodynamics of JSKN033 in Patients With Advanced Non-Small Cell Lung Cancer","sponsor":"Jiangsu Alphamab Biopharmaceuticals Co., Ltd","enrolled":160,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07283198/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"company":[{"id":"alphamab","kind":"company","name":"Alphamab Oncology","route":"/companies/alphamab/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}