{"entity":{"id":"nct07284992","kind":"trial","name":"SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Shandong Provincial Hospital, now recruiting.","summary":"SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC is a phase 2, randomised interventional study registered as NCT07284992 by Shandong Provincial Hospital, with a registry enrolment figure of 208 participants, started 2025-09-12 and due to reach its primary completion in 2028-11-30. Interventions recorded: short-term radiotherapy combined with Adebrelimab and capox; long-term radiotherapy combined with Adebrelimab and capox. Conditions listed: Rectal Cancer; Advanced Stage Colorectal Cancer; Radiotherapy. Primary outcome: CR rate. Colorectal eligibility wording from the registry: \"Patients diagnosed as rectal adenocarcinoma by primary biopsy and histopathological examination;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07284992","url":"https://clinicaltrials.gov/study/NCT07284992"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07284992","phase":"2","setting":"Total Neoadjuvant Treatment With Short-course Radiotherapy Versus Long-course Radiotherapy Followed by PD-L1 Inhibitor Plus Capecitabine-Oxaliplatin in Patients With Locally Advanced Rectal Cancer: a Multi-centres, Open-label, Phase 2, Randomized Controlled Trial","sponsor":"Shandong Provincial Hospital","enrolled":208,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07284992/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}