{"entity":{"id":"nct07291401","kind":"trial","name":"Radiotherapy Plus CAPOX, and Iparomlimab and Tuvonralimab (QL1706) as Neoadjuvant Therapy for LARC","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Zhongnan Hospital, now recruiting.","summary":"Radiotherapy Plus CAPOX, and Iparomlimab and Tuvonralimab (QL1706) as Neoadjuvant Therapy for LARC is a phase 2, interventional study registered as NCT07291401 by Zhongnan Hospital, with a registry enrolment figure of 108 participants, started 2025-11-01 and due to reach its primary completion in 2027-01-01. Interventions recorded: lparomlimab and Tuvonralimab Injection and CPAOX and radiotherapy. Conditions listed: Rectal Cancer Patients. Primary outcome: Complete response (CR). Colorectal eligibility wording from the registry: \"* (1) The patient is histologically diagnosed with rectal adenocarcinoma\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07291401","url":"https://clinicaltrials.gov/study/NCT07291401"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07291401","phase":"2","setting":"Neoadjuvant Chemoradiotherapy Combined Cith Iparomlimab and Tuvonralimab (QL1706) Therapy for Locally Advanced Rectal Cancer：a Single-center, Prospective, Single-arm, Open-label, Phase II Clinical Trial","sponsor":"Zhongnan Hospital","enrolled":108,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07291401/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}