{"entity":{"id":"nct07293351","kind":"trial","name":"A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal ","aka":[],"tldr":"A phase 1/2 trial of PM8002, Ipilimumab, Cabozantinib in renal cell carcinoma, run by Bristol-Myers Squibb, now recruiting.","summary":"A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208) is a phase 1/2 interventional study registered as NCT07293351 by Bristol-Myers Squibb, with 474 participants planned, started 2026-03-26 and due to reach its primary completion in 2029-11-28. Interventions recorded: Pumitamig, Ipilimumab, Cabozantinib, Casdatifan. Conditions listed: Advanced Renal Cell Carcinoma (RCC). No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07293351","url":"https://clinicaltrials.gov/study/NCT07293351"}],"tags":["ctgov-ingest"],"related":[],"cancers":["rcc"],"sections":[],"technologies":[],"targets":[],"drugs":["pm8002","ipilimumab","cabozantinib"],"companies":["bms"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT07293351","phase":"1/2","setting":"ROSETTA RCC-208: A Phase 1/2 Open-label, Multi-center, Randomized Study of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC)","sponsor":"Bristol-Myers Squibb","enrolled":474,"outcomes":[]},"route":"/trials/nct07293351/","neighbours":{"cancer":[{"id":"rcc","kind":"cancer","name":"Renal cell carcinoma","route":"/cancers/rcc/"}],"drug":[{"id":"cabozantinib","kind":"drug","name":"Cabozantinib","route":"/drugs/cabozantinib/"},{"id":"ipilimumab","kind":"drug","name":"Ipilimumab","route":"/drugs/ipilimumab/"},{"id":"pm8002","kind":"drug","name":"PM8002","route":"/drugs/pm8002/"}],"company":[{"id":"bms","kind":"company","name":"Bristol Myers Squibb","route":"/companies/bms/"}]}}