{"entity":{"id":"nct07294261","kind":"trial","name":"Garsorasib In KRAS G12C Mutant Locally Advanced and Metastatic NSCLC","aka":[],"tldr":"A phase 2 trial in lung cancer, run by Sun Yat-sen University, not yet recruiting.","summary":"Garsorasib In KRAS G12C Mutant Locally Advanced and Metastatic NSCLC is a phase 2, randomised interventional study registered as NCT07294261 by Sun Yat-sen University, with a registry enrolment figure of 69 participants, started 2025-12-23 and due to reach its primary completion in 2028-10-30. Interventions recorded: Garsorasib, Benmelstobart, Anlotinib; Benmelstobart, Anlotinib; Garsorasib, Cetuximab Beta Injection. Conditions listed: Local Advanced or Metastatic NSCLC. Primary outcome: Overall response rate (ORR); DoR. Lung eligibility wording from the registry: \"Histologically confirmed IIIB-IV NSCLC\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT07294261","url":"https://clinicaltrials.gov/study/NCT07294261"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["kras-g12c-nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["sino-biopharm"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07294261","phase":"2","setting":"A Multicenter, Prospective Clinical Study Evaluating Goselasib Combination Therapy for First-Line Treatment of KRAS G12C Locally Advanced or Metastatic Non-Small Cell Lung Cancer","sponsor":"Sun Yat-sen University","enrolled":69,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07294261/","neighbours":{"cancer":[{"id":"kras-g12c-nsclc","kind":"cancer","name":"KRAS G12C-mutant non-small-cell lung cancer","route":"/cancers/kras-g12c-nsclc/"}],"company":[{"id":"sino-biopharm","kind":"company","name":"Sino Biopharmaceutical (Chia Tai Tianqing)","route":"/companies/sino-biopharm/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}