{"entity":{"id":"nct07301229","kind":"trial","name":"A Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Pancreatic Cancer","aka":[],"tldr":"A phase 2 trial in pancreatic cancer, run by Shanghai Henlius Biotech, not yet recruiting.","summary":"A Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Pancreatic Cancer is a phase 2, randomised interventional study registered as NCT07301229 by Shanghai Henlius Biotech, with a registry enrolment figure of 100 participants, started 2025-12-29 and due to reach its primary completion in 2028-02-21. Interventions recorded: HLX43 DOSE 1 (2.5 mg/kg); HLX43 DOSE 2 (3.0 mg/kg). Conditions listed: Pancreatic Ductal Adenocarcinoma (PDAC). Primary outcome: ORR; PFS. Pancreatic eligibility wording from the registry: \"Histologically or cytologically confirmed, unresectable locally advanced or metastatic pancreatic ductal adenocarcinoma (PDAC),who has failed at least one prior line of standard systemic therapy\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07301229","url":"https://clinicaltrials.gov/study/NCT07301229"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac","metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07301229","phase":"2","setting":"A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Subjects With Advanced Pancreatic Cancer","sponsor":"Shanghai Henlius Biotech","enrolled":100,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07301229/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"},{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}